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Underdiagnosis of Sleep Apnea Syndrome in US Communities.
ABSTRACT
We hypothesize that clinical recognition rates for obstructive sleep apnea-hypoapnea
syndrome (OSAHS) are influenced by comorbidity and demographic factors. Data on medical disorders, symptoms of
sleep disorders, and cardiovascular risk factors gathered from 15,699 individuals in the Sleep Heart Health
Study were compared. Participants were classified into three groups: those with a self-reported physician
diagnosis of OSAHS, those with self-reported physician-diagnosed and -treated OSAHS, and those reporting both
frequent snoring and daytime sleepiness (two-symptom group). Among all participants, 4.1% reported two
symptoms (range across sites: 1.55 to 7.23%), whereas 1.6% reported a physician diagnosis of OSAHS (range:
0.66 to 2.88%) and 0.6% reported physician diagnosis and treatment (range: 0.11 to 0.88%). Recognized OSAHS
groups were similar to the two-symptom group in age, having a sleeping partner, measured blood pressure, total
cholesterol, and race. In a logistic model that included age along with characteristics found to vary
significantly among the three groups (gender, body mass index [BMI], high-density lipoprotein cholesterol
levels, hypertension), only male gender and BMI were increased in those with physician-diagnosed and -treated
OSAHS. We conclude that disparities (especially in women and in those with lower BMI) exist between current
recognition rates for OSAHS and the estimated prevalence by symptom report across the United States.
Keywords: Sleep apnea - clinical diagnosis - prevalence - cardiovascular risk